The ambition of the NCCR Microbiomes is to leap to a new level of understanding that enables rational management of microbiomes for health, environment and engineering applications.
Mission
The NCCR Microbiomes brings together an interdisciplinary consortium made up of 20 research groups from six institutions across Switzerland.
Network
Researchers on the NCCR Microbiomes are engaged in combating the COVID-19 pandemic, through the development of testing methods, vaccines, and platforms for sharing knowledge and resources.
News
The NCCR Microbiomes co-organises the #NCCRWomen campaign, which highlights the central role that women play in all fields of research in Switzerland.
#NCCRWomen

Enabling rational management of microbes for health, environment and engineering applications

The Swiss National Centre of Competence in Research (NCCR) Microbiomes brings together a unique and interdisciplinary research program with experimental and clinical microbiome studies. Combining computational, modeling, engineering and synthetic approaches, the Centre aims to understand the unifying principles of microbiome functioning, to develop tools to diagnose microbiome status, and to devise strategies to intervene and restore imbalanced microbiomes. Its scope encompasses microbial communities in human, animals, plants, as well as in natural and industrial environments.

The NCCR Microbiomes comprises 20 research teams from across Switzerland: the University of Lausanne (leading house), ETH Zurich (co-leading house), EPF Lausanne, the University of Zurich, the University of Bern, and Lausanne University Hospital (CHUV). It brings together internationally recognized experts in human infections, animal gut and plant microbiomes, genomics and computational biology, applied and environmental microbiology, and microbial ecology and evolution. Launched in 2020, the NCCR Microbiomes is funded by the Swiss National Science Foundation.

NCCR BROCHURE (en) BROCHURE PRN (fr) BROSCHÜRE NFS (de)

Research

An interdisciplinary approach

The NCCR Microbiomes integrates computational biology, bioinformatics, experimental approaches and medical microbiology with a focus on synthetic and engineering applications.

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Latest publications

A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
Diard, M., Bakkeren, E., [...], Hardt, W.-D., Slack, E. (2021).
https://doi.org/10.1038/s41564-021-00911-1
High throughput sequencing provides exact genomic locations of inducible prophages and accurate phage-to-host ratios in gut microbial strains
Zünd, M., Ruscheweyh, H.-J., Field, C. M., Meyer, N., Cuenca, M., Hoces, D., Hardt, W.-D., Sunagawa, S. (2021).
https://doi.org/10.1186/s40168-021-01033-w
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